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Berberine Breakthrough

Bioptimizers • SKU#: BZR-BER60
1 5
  • Description
  • How to Use
  • Benefits

Berberine Breakthrough contains GlucoVantage®, the first commercially available brand of Dihydroberberine, an active metabolite of berberine. GlucoVantage® dihydroberberine has been shown to be 5x more absorbable than standard berberine and 2x longer lasting. Additionally, dihydroberberine helps overcome limitations of standard berberine, such as digestive distress.

This Is What Next-Level Berberine Looks Like

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Supports Metabolic Balance
When your metabolism is supported, everything feels more balanced. This formula helps support healthy glucose metabolism and overall metabolic function—so you can feel more like yourself.*

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Everyday Energy Support
Steady glucose availability supports consistent daily energy. This formula helps maintain healthy blood sugar levels already within the normal range to support steady energy throughout the day.*

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Supports You as You Age
Metabolic and antioxidant support work together to help support vitality and resilience over time—aging support you can feel good about.*

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Supports Consistent Energy Levels
Helps maintain healthy blood sugar levels already within the normal range, supporting more even energy and fewer mid-day dips.*



2 capsules a day

GlucoVantage® Versus Standard Berberine

  • 20x greater area under the curve (AUC)
  • 5x more bioavailable / absorbable
  • 2x longer-lasting (8 hours vs. 4 hours)

Higher bioavailability of dihydroberberine means fewer capsules are needed to obtain the benefits of berberine.

  • Support for blood sugar levels already within normal limits*
  • Promotion of improved carbohydrate tolerance*
  • Support for overall body composition*

  • Supplement Facts

    Serving Size: 2 capsules
    Servings Per Container: 30

    Amount per serving % Daily Value
    Biotin 2 mg 6667%
    Chromium (as chromium picolinate) 400 mcg 1143%
    Proprietary Blend-CyanthOx™30 Hippophae rhamnoides L (fruit) Extract (30% proanthocyanidins) Irvingia gabonensis (seed) Naringin Benfotiamine R-Alpha Lipoic Acid Banaba (leaf) Extract (20% corosolic acid) Gymnema sylvestre (leaf) Extract Fucoxanthin 10% 638 mg **
    Bitter Melon (fruit) Extract (10% charantin) 200 mg **
    Gluco Vantage® Dihydroberberine 100 mg **
    Cinnulin PF® Cinnamon (bark) 20:1 Extract 100 mg **
    Innoslim® (Blend of Panax notoginseng and Astragalus membranaceus) 75 mg **
    *Daily Value not established

    Ingredients: Hypromellose (capsule), rice fiber, rice extract blend.

$52.99 / 60
$52.99 / 60
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  • Dr. Mark Hyman
    ★★★★★ Trusted by thousands of patients
    Dr. Mark Hyman Approved
    "After 30 years in functional medicine, I only endorse supplements that meet my rigorous standards."
    Doctor Formulated Tested for Purity No Gluten
    Related Health Categories
    Blood Sugar Support Digesting Carbohydrates
  • Safety

    *These statements have not been evaluated by the FDA. This product is not intended to diagnose, treat, cure, or prevent any disease.

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